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ea0049ep1180 | Male Reproduction | ECE2017

Study of CDX-2 VDR gene polymorphisms in male infertility

Vladoiu Suzana , Draganescu Daniela Dinu , Botezatu Anca , Manda Dana , Oros Sabina , Rosca Roxana , Anton Gabriela , Paun Diana , Badiu Corin

The CDX2 VDR polymorphism (rs11568820) is located in the promoter region of exon 1 in the 5′-untranslated region of the VDR gene.Objective: The current investigation examines the association between CDX2 VDR polymorphism and male infertility.Subjects and methods: The study was conducted on 69 infertile men, aged between 20 and 50 years, divided into three groups, based on spermatic parameters: group with azoospermia (19 subje...

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ea0090p718 | Reproductive and Developmental Endocrinology | ECE2023

Correlation between both serum and seminal fluid vitamin D levels and vitamin D receptor CDX polymorphism in male infertility

Vladoiu Suzana , Botezatu Anca , Muresan Andrei , Albulescu Adrian , Popa Oana-Monica , Alina Fudulu , Adriana Ples , Stancu Cristina , Iulia Virginia Iancu , Badiu Corin , Draganescu Daniela Dinu

Vitamin D (VD) now considered a steroid hormone, has been correlated with male reproductive disorders. The activity of VD is mediated through its receptor (VDR), distributed in various tissues including reproductive tissues. VDR polymorphism located in the promoter region of the gene, rs17883968 (Cdx2) G → A associated with transcriptional activity. The aim of this study was to assess both seminal and serum VD levels in a group of infertile patients (n=87, media...

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Endocrine Abstracts

Study of CDX-2 VDR gene polymorphisms in male infertility

Correlation between both serum and seminal fluid vitamin D levels and vitamin D receptor CDX polymorphism in male infertility

BiosciAbstracts